Antibacterial, muscle relaxant, and hypnotic effects of seeds of Peganum harmala on mice
نویسندگان
چکیده
منابع مشابه
Cytotoxicity of alkaloids isolated from Peganum harmala seeds.
ETHNOPHARMACOLOGICAL RELEVANCE Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several tumor cell lines in vitro and has antitumor effect in a tumor model in vivo. The present investigation was aimed at extending our previous studies in identifying the components i...
متن کاملEvaluation of Antidiabetic and Antihyperlipidemic Effects of Peganum harmala Seeds in Diabetic Rats
The present study was carried out to investigate the antidiabetic and antihyperlipidemic properties of hydroalcoholic extract of Peganum harmala in streptozotocin-induced diabetic male rats. In an experimental study, 64 normal Wistar albino male rats (200-230 g) were randomly divided into 8 groups. Control and diabetic rats were treated with normal saline and three different doses (30, 60, and ...
متن کاملIn vitro and in vivo effects of Peganum harmala L. seeds extract against influenza A virus
Objective Influenza A virus infections are still a major health problem and the choices available for the control and treatment of the disease are limited. This research evaluated in vitro and in vivo antiviral effects of Peganum harmala L. seeds (PHS) extract against influenza A virus. Materials and Methods In this research, in vitro anti-influenza A virus activity of the extract was assesse...
متن کاملVasorelaxant effects of harmine and harmaline extracted from Peganum harmala L. seeds in isolated rat aorta.
The present work describes the mechanisms involved in the vasorelaxant effect of harmine and harmaline. These alkaloids induce in a dose-dependent manner the relaxation in the aorta precontracted with noradrenaline or KCl. However, the removal of endothelium or pre-treatment of intact aortic ring with L-NAME (inhibitor of NOSe synthetase) or with indomethacin (non-specific inhibitor of cyclo-ox...
متن کاملPharmacological Effects of Peganum harmala Seeds Extract on Isolated Rat Uterus
The effects of hydroalcoholic extract of Peganum harmala seeds (EPS) on spontaneous rhythmic contractions of isolated rat uterine was investigated in this study. EPS was tested on the isolated uterus and endometrium free (i.e. stripped myometrium) preparations. EPS was found to exhibit significant spontaneous contractions of the uterus and stripped myometrium relative to the solv...
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ژورنال
عنوان ژورنال: African Journal of Microbiology Research
سال: 2019
ISSN: 1996-0808
DOI: 10.5897/ajmr2014.7297